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Glossary Genetics / Term

substitution

Replacement of one nucleotide in a DNA sequence by another nucleotide or replacement of one amino acid in a protein by another amino acid.

Dr. Leslie Biesecker, of the National Human Genome Research Institute's Laboratory of Genetic Disease Research, defines substitution.

Related terms: amino acids, inherited, mutation, nucleotide, protein.

Permanent link substitution - Modification date 2020-01-16 - Creation date 2020-01-16


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