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Glossary Liquid chromatography / Term

Diol phase

A stationary phase useful in both normal and reversed-phase chromatography. Consists of a diol structure (two -OH groups on adjacent carbon atoms in an aliphatic chain). Less polar than silica stationary phases used in normal-phase chromatography has been used for the reversed-phase separation of proteins and polypeptides.


A hydrophilic phase that is useful in normal and reversed phase. It is a diol structure (two –OH groups on adjacent carbon atoms in an aliphatic chain). In normal-phase work, it is less polar than silica. It has been used to separate proteins and polypeptides in reversed-phase chromatography.

Permanent link Diol phase - Modification date 2023-01-29 - Creation date 2020-03-16


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