(NSAIDs) These drugs block the body's production of prostaglandins, substances that mediate pain and inflammation. NSAIDs relieve the pain from chronic and acute inflammatory conditions, including arthritis and other rheumatic conditions, and pain associated with injuries, bursitis, tendinitis, and dental problems. NSAIDs also relieve pain associated with noninflammatory conditions. Generic and brand names of NSAIDs include aspirin (Bayer and Bufferin), ibuprofen (Advil, Nuprin, and Motrin), tometin (Tolectin), naproxen (Naprosyn), and piroxicam (Feldene).